ASUS PRIME B650M-A WiFi

A CPU only physically fits motherboards built for its socket (e.g. AM5, LGA1700). This is the first compatibility check in any build. Server CPUs use entirely separate socket families (e.g. AMD SP5, Intel LGA4677) and need a server-specific motherboard — desktop and server platforms are never interchangeable.

Motherboards support one memory generation — DDR4 or DDR5, not both. RAM speed above the board's supported limit will run at a lower speed.

NVMe drives need an M.2 slot with a matching PCIe generation to hit their rated speed; SATA drives need a SATA header and cable.

ATX, Micro-ATX, and Mini-ITX motherboards each need a case built to support that mounting size.

Internal Wi-Fi adapters need a free PCIe slot and, usually, motherboard antenna headers.

ECC (error-correcting) memory only works if both the CPU and motherboard explicitly support it. Most consumer gaming boards don't — ECC is mainly a server/workstation feature. Using ECC RAM in a board that doesn't support it usually just makes it run as non-ECC.